Reading List - Antibodies

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Both L., Banyard A.C., van Dolleweerd C., Wright E., Ma J.K., and Fooks A.R. (2013) Monoclonal antibodies for prophylactic and therapeutic use against viral infections. Vaccine 31, 1553–1559.

Carroll M.C. (2008) Complement and humoral immunity. Vaccine 26, I28–I33.

Chan A.C. and Carter P.J. (2010) Therapeutic antibodies for autoimmunity and inflammation. Nature Reviews Immunology 10, 301–316.

Chen K., Xu W., Wilson M., et al. (2009) Immunoglobulin D enhances immune surveillance by activating antimicrobial, proinflammatory and B cell‐stimulating programs in basophils. Nature Immunology 10, 889–898.

Diebolder C.A., Beurskens F.J., de Jong R.N., et al. (2014) Complement is activated by IgG hexamers assembled at the cell surface. Science 343, 1260–1263.

Di Noia J.M. and Neuberger M.S. (2007) Molecular mechanisms of antibody somatic hypermutation. Annual Review of Biochemistry 76, 1–22.

Drinkwater N., Cossins B.P., Keeble A.H., et al. (2014) Human immunoglobulin E flexes between acutely bent and extended conformations. Nature Structural and Molecular Biology 21, 397–404.

Ducancel F. and Muller B.H. (2012) Molecular engineering of antibodies for therapeutic and diagnostic purposes. MAbs 4, 445–457.

Holdom M.D., Davies A.M., Nettleship J.E., et al. (2011) Conformational changes in IgE contribute to its uniquely slow dissociation rate from receptor Fc εRI. Nature Structural and Molecular Biology 18, 571–576.

Hozumi N. and Tonegawa S. (1976) Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions. Proceedings of the National Academy of Sciences of the USA 73, 3628–3632.

IMGT database: www.imgt.org/

Jung D. and Alt F.W. (2004) Unraveling V(D)J recombination: insights into gene regulation. Cell 116, 299–311.

Jung D., Giallourakis C., Mostoslavsky R., and Alt F.W. (2006) Mechanism and control of V(D)J recombination at the immunoglobulin heavy chain locus. Annual Review of Immunology 24, 541–570.

Maizels N. (2005) Immunoglobulin gene diversification. Annual Review of Genetics 39, 23–46.

Maki R., Traunecker, A., Sakano, H., Roeder, W., and Tonegawa, S. (1980) Exon shuffling generates an immunoglobulin heavy chain gene. Proceedings of the National Academy of Sciences of the USA 77, 2138–2142.

Martin W.L., West A.P. Jr, Gan L., and Bjorkman P.J. (2001) Crystal structure at 2.8 Å of an FcRn/heterodimeric Fc complex: mechanism of pH‐dependent binding. Molecular Cell 7, 867–877.

Matsuda F. and Honjo T. (1996) Organization of the human immunoglobulin heavy‐chain locus. Advances in Immunology 62, 1–29.

Matthews A.J., Zheng S., DiMenna L.J., and Chaudhuri J. (2014) Regulation of immunoglobulin class‐switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long‐range DNA repair. Advances in Immunology 122, 1–57.

Min I.M. and Selsing E. (2005) Antibody class switch recombination: roles for switch sequences and mismatch repair proteins. Advances in Immunology 87, 297–328.

Nemazee D. (2006) Receptor editing in lymphocyte development and central tolerance. Nature Reviews Immunology 6, 728–740.

Neuberger M.S. (2008) Antibody diversification by somatic mutation: from Burnet onwards. Immunology and Cell Biology 86, 124–132.

Nimmerjahn F. and Ravetch J.V. (2011) Fc γRs in health and disease. Current Topics in Microbiology and Immunology 350, 105–125.

Nimmerjahn F. and Ravetch J.V. (2012) Translating basic mechanisms of IgG effector activity into next generation cancer therapies. Cancer Immunity 12, 13.

Padlan E.A. (1994) Anatomy of the antibody molecule. Molecular Immunology 31, 169–217.

Padlan E.A. (1996) X‐ray crystallography of antibodies. Advances in Protein Chemistry 49, 57–133.

Parren P.W. and Burton D.R. (2001) The antiviral activity of antibodies in vitro and in vivo. Advances in Immunology 77, 195–262.

Peled J.U., Kuang F.L., Iglesias‐Ussel M.D., et al. (2008) The biochemistry of somatic hypermutation. Annual Review of Immunology 26, 481–511.

Perlot T. and Alt F.W. (2008) Cis‐regulatory elements and epigenetic changes control genomic rearrangements of the IgH locus. Advances in Immunology 99, 1–32.

Rath T., Kuo T.T., Baker K., et al. (2013) The immunologic functions of the neonatal Fc receptor for IgG. Journal of Clinical Immunology 33 (Suppl 1), S9–S17.

Roopenian D.C. and Akilesh S. (2007) FcRn: the neonatal Fc receptor comes of age. Nature Reviews Immunology 7, 715–725.

Roth D.B. (2003) Restraining the V(D)J recombinase. Nature Reviews Immunology 3, 656–666.

Schroeder H.W. Jr. and Cavacini L. (2010) Structure and function of immunoglobulins. Journal of Allergy and Clinical Immunology 125, S41–S52.

Scott A.M., Allison J.P., and Wolchok J.D. (2012) Monoclonal antibodies in cancer therapy. Cancer Immunity 12, 14.

Strugnell R.A. and Wijburg, O.L.C. (2010) The role of secretory antibodies in infection immunity. Nature Reviews Microbiology 8, 656–667.

Swanson P.C. (2004) The bounty of RAGs: recombination signal complexes and complex outcomes. Immunological Reviews 200, 90–114.

Swartz, M.A., Hirosue S., and Hubbell J.A. (2012) Engineering approaches to immunotherapy. Science Translational Medicine 4, 148rv9.

Vincent K.J. and Zurini M. (2012) Current strategies in antibody engineering: Fc engineering and pH‐dependent antigen binding, bispecific antibodies and antibody drug conjugates. Biotechnology Journal 7, 1444–1450.

Ward E.S. (2004) Acquiring maternal immunoglobulin; different receptors, similar functions. Immunity 20, 507–508.

Woof J.M. and Burton D.R. (2004) Human antibody‐Fc receptor interactions illuminated by crystal structures. Nature Reviews Immunology 4, 89–99.

Woof J.M. and Kerr M.A. (2006) The function of immunoglobulin A in immunity. Journal of Pathology 208, 270–282.

Roitt's Essential Immunology

Thirteenth Edition

Reading List - Antibodies